Trophon Logo White Gradient (png)

Microbial Defence

trophon® technology goes further to deliver the broadest* patient protection.
Trophon Logo White Gradient (png)

Microbial Defence

trophon® technology goes further to deliver the broadest* patient protection.

An extensive list of pathogens have been implicated in healthcare-associated infections (HAIs). High level disinfection (HLD) of semi-critical medical devices such as ultrasound probes is an essential part of the fight against HAIs.

Nanosonics has conducted extensive laboratory testing to validate the effectiveness of trophon devices and its sonicated disinfectant mist technology

As a result, trophon devices are the only automated HLD technology for transvaginal, transrectal and surface ultrasound probes to meet mandatory microbial efficacy test requirements for both CE mark and FDA registration.

This includes testing that meets the required EN, ASTM and AOAC standards to demonstrate:1-3

  • Bactericidal efficacy
  • Virucidal efficacy (enveloped and non-enveloped viruses)
  • Fungicidal efficacy
  • Mycobactericidal efficacy

Going Beyond the Mandatory Requirements

In addition to mandatory testing, trophon technology is demonstrated to eliminate an extended range of clinically relevant pathogens including:

  • Multi-drug resistant bacteria, such as MRSA
  • Blood borne viruses, such as HCV
  • Sexually transmitted pathogens, such as Chlamydia
  • Clostridium difficile spores
Vegetative bacteria Fungi
Staphylococcus aureus Candida albicans
Pseudomonas aeruginosa Aspergillus niger
Enterococcus hirae Viruses
Carbapenem-resistant Escherichia coli
Polio virus type 1
Methicillin-resistant Staphylococcus aureus Herpes simplex virus type 1
Vancomycin-resistant Enterococcus Hepatitis A virus
Neisseria gonorrhoea Adenovirus type 5
Chlamydia trachomatis Human hepatitis B virus surrogate (duck hepatitis B virus)
Mycobacteria Human immunodeficiency virus type 1
Mycobacterium terrae Murine norovirus
Mycobacterium avium Norovirus surrogate (feline calcivirus)
Bacterial endospores Human papillomavirus HPV16
Geobacillus stearothermophilus Human papillomavirus HPV18
Bacillus subtilis Hepatitis C virus surrogate (Bovine viral diarrhoea virus)
Bacillus cereus  
Clostridium difficile  

The trophon Device Performance Demonstrated in Clinical Settings

The trophon device outperforms other methods of disinfection that have been tested in similar clinical settings:4,5

  • Low level disinfection (LLD) wipes fail to systematically remove bacterial contamination from patient-used ultrasound probes.4
  • UVC disinfection also fails to systematically remove bacterial contamination from ultrasound probes with no significant difference in performance to LLD wipes.6
  • 80% of probe handles are contaminated with bacteria after soaking in glutaraldehyde when the handle is not immersed, per typical practice.5
“We chose the trophon system because it stood out from the rest. We like the efficacy of the product and the fact it’s proven to kill high-risk, cancer-causing HPV”
Lisa Antsy
Manager of Medical Reprocessing
Grand River Hospital in Ontario, Canada

* Broadest efficacy spectrum as compared to ultrasound probe disinfection with UVC and ClO2 wipes systems.

The trophon technology family includes trophon EPR devices and trophon2 devices which share the same core technology of 'sonically activated' hydrogen peroxide.

  1. Vickery, K., et al. (2014). "Evaluation of an automated high-level disinfection technology for ultrasound transducers." J Infect Public Health 7(2): 153-160.
  2. Becker, B., et al. (2017). "Virucidal efficacy of a sonicated hydrogen peroxide system (trophon(®) EPR) following European and German test methods." GMS Hygiene and Infection Control 12: Doc02.
  3. Ryndock, E., et al. (2016). "Susceptibility of HPV16 and 18 to high level disinfectants indicated for semi-critical ultrasound probes." J Med Virol 88(6):
  4. Buescher, D. L., et al. (2016). "Disinfection of transvaginal ultrasound probes in a clinical setting: comparative performance of automated and manual reprocessing methods." Ultrasound Obstet Gynecol 47(5): 646-651.
  5. Ngu, A., et al. (2015). "Reducing Transmission Risk Through High-Level Disinfection of Transvaginal Ultrasound Transducer Handles." Infect Control Hosp Epidemiol 36(5): 1-4.
  6. Schmitz, J., et al. (2019). "Disinfection of Transvaginal Ultrasound Probes by Ultraviolet C – A Clinical Evaluation of Automated and Manual Reprocessing Methods." Ultraschall in Med 2019; doi: 2010.1055/a-0874-1971. [Epub ahead of print].
Demonstrated Compliance